探讨食管乳头状瘤(EP)对幽门螺杆菌(Hp)感染的抑制作用，为临床早期诊断食管乳头状瘤并科学治疗提供依据。

通过内镜的常规检查及Hp检测，回顾性分析佛山市高明区人民医院消化内镜中心自2015年3～9月以来患者的情况，选取食管乳头状瘤患者62例为观察组，均经我院胃镜检查初步诊断，对照组为同时期我院行胃镜检查诊断为慢性浅表性胃炎的患者1 000例。均应用尿素[¹³C]呼气试验进行Hp检测，从而判断是否感染Hp。组间采用对比研究，分析两组Hp阳性感染率的统计学差异。

观察组Hp阳性感染率为22.58%(14/62)，对照组Hp阳性感染率为62.4%(624/1 000)，两组相比差异有统计学意义(P<0.01)。两组性别、年龄方面差异无统计学意义(P>0.05)。

Hp感染对食管乳头状瘤的发病可能起一定的抑制作用。

To study the esophageal papilloma(EP)of Helicobacter pylori(Hp)infection inhibition, for the early clinical diagnosis of esophageal papilloma and provide scientific basis for treatment.

through the routine inspection and detection of Hp endoscopy, retrospective analysis of Gaoming District of Foshan City People′s Hospital of digestive endoscopy center since March 2015 to patients since September 2015, selection of esophageal papilloma in 62 cases of the observation group were treated by gastroscopy, the initial diagnosis, the control group for the same period in our hospital for gastroscopy diagnosis for 1 000 cases of chronic superficial gastritis patients.Both the application of urea breath test for detection of [¹³C]Hp, in order to determine whether infection the comparative study between the Hp group, statistical analysis of differences between the two groups of Hp positive infection rate.

in the observation group, Hp positive rate was 22.58%(14/62), the control group Hp positive infection rate was 62.4%(624/1 000), the two group.There were statistically significant differences between the groups(P<0.01). There was no significant difference in age between the two groups(P>0.05).

Hp infection may play a certain role in the pathogenesis of esophageal papilloma.