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中华胃食管反流病电子杂志 ›› 2025, Vol. 12 ›› Issue (04) : 160 -164. doi: 10.3877/cma.j.issn.2095-8765.2025.04.006

综述

基于"门系统"探讨抗反流屏障构成与手术修复机制
赵磊1, 张晓宁1, 钟华2, 邓文兵2, 唐洪波3, 黄秋林1,()   
  1. 1421001 湖南衡阳,南华大学附属第一医院胃肠外科
    2421001 湖南衡阳,南华大学附属第一医院消化内科
    3421001 湖南衡阳,南华大学附属第一医院耳鼻喉科
  • 收稿日期:2025-08-28 出版日期:2025-11-15
  • 通信作者: 黄秋林
  • 基金资助:
    国家自然科学基金青年项目(81900488); 湖南省卫生健康高层次人才重大科研专项(20231526); 湖南省自然科学基金项目(2025JJ81050); 湖南省自然科学基金项目(2023JJ60369); 湖南省卫健委科研课题(202104010694)

Discussion on anti reflux barrier composition and surgical repair mechanism based on "door system"

Lei Zhao1, Xiaoning Zhang1, Hua Zhong2, Wenbing Deng2, Hongbo Tang3, Qiulin Huang1,()   

  1. 1Department of Gastrointestinal Surgery, the First Affiliated Hospital of University of South China, Hengyang Medical School, University of South China, Hengyang 421001, China
    2Department of gastroenterology and Hepatology, the First Affiliated Hospital of University of South China, Hengyang Medical School, University of South China, Hengyang 421001, China
    3Department of Otorhinolaryngologic, the First Affiliated Hospital of University of South China, Hengyang Medical School, University of South China, Hengyang 421001, China
  • Received:2025-08-28 Published:2025-11-15
  • Corresponding author: Qiulin Huang
引用本文:

赵磊, 张晓宁, 钟华, 邓文兵, 唐洪波, 黄秋林. 基于"门系统"探讨抗反流屏障构成与手术修复机制[J/OL]. 中华胃食管反流病电子杂志, 2025, 12(04): 160-164.

Lei Zhao, Xiaoning Zhang, Hua Zhong, Wenbing Deng, Hongbo Tang, Qiulin Huang. Discussion on anti reflux barrier composition and surgical repair mechanism based on "door system"[J/OL]. Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition), 2025, 12(04): 160-164.

抗反流屏障解剖异常和功能失调是胃食管反流病发生的重要原因。本文以"门系统"类比抗反流屏障构成,强调抗反流屏障不是单一的解剖单元,而是由食管下括约肌(门板)、膈肌脚(门框)、膈食管韧带(铰链)和His角、胃食管阀瓣(门把手)等多结构构成的有机整体,精密结合,协同作用。膈食管韧带连接食管下括约肌与膈肌脚构成解剖上相互重叠、功能上互相叠加的空间结构,即"coincide"结构。His角和胃食管阀瓣是从胃壁内外不同视角描述的同一抗反流结构,即抗反流瓣复合体。"coincide"结构和抗反流瓣复合体相互交联,发挥抗反流作用,二者构成抗反流屏障的主体结构。食管裂孔疝是导致胃食管反流病发生和发展的重要解剖病因。食管裂孔疝通过膈肌脚扩大、膈食管筋膜松弛、胃食管结合部上移,导致食管下括约肌压力下降、胃食管阀瓣疏松、His角变钝,从而破坏抗反流屏障解剖结构和整体功能。基于这一整体论视角,文章论证了抗反流修复手术的本质是对抗反流屏障这一有机复合体的精准修复:修复食管下括约肌与膈肌脚连同膈食管韧带构成的"coincide"结构,恢复腹段食管的长度,同时重建His角和胃食管阀瓣组成的抗反流瓣复合体,通过"四位一体"重建实现抗反流屏障结构与功能一体化重建,恢复其多构件精密组合、多结构协同工作的有机整体功能。

Anatomical abnormalities and dysfunction of anti reflux barrier are important causes of gastroesophageal reflux disease. This paper proposes to use the "door system" as a metaphor for the composition of the anti reflux barrier, emphasizing that the anti reflux barrier is not a single anatomical unit, but an organic whole with multiple structures, such as the lower esophageal sphincter (door plate), diaphragm foot (door frame), phrenic esophageal ligament (hinge), his angle, gastroesophageal valve flap (door handle), which are precisely combined and coordinated with each other. The phrenic esophageal ligament connects the lower esophageal sphincter (LES) with the diaphragm foot to form a spatial structure that overlaps anatomically and functionally, namely the "coincide" structure. The his angle and gastroesophageal valve flap are the same antireflux valve complex described from different perspectives inside and outside the gastric wall. The "coincide" structure and the anti regurgitant valve complex are cross-linked to each other to play an anti regurgitant role, and they constitute the main structure of the anti regurgitant barrier. Hiatal hernia is an important anatomic etiology leading to the occurrence and development of gastroesophageal reflux disease. Esophageal hiatal hernia through the diaphragm foot expansion, diaphragmatic esophageal fascia relaxation, gastroesophageal junction upward, resulting in lower esophageal sphincter pressure drop, gastroesophageal valve flap loose, his angle blunt, resulting in the systematic destruction of the anatomical structure of the anti reflux barrier, resulting in the overall obstacle of anti reflux function. Based on this holistic perspective, the article demonstrates that the essence of anti reflux repair surgery is the precise repair of the organic complex of anti reflux barrier: repair the "coincide" structure consisting of the lower esophageal sphincter and the diaphragm foot together with the phrenic esophageal ligament, restore the length of the abdominal esophagus, and rebuild the anti reflux valve complex consisting of his angle and gastroesophageal valve flap, namely the door handle system, to achieve the restoration of anti reflux structure function integration through "four in one" reconstruction. The destroyed anti reflux barrier was reconstructed into an anti reflux organic complex with precise combination of anatomic components and functional cooperation of multiple structures.

图1 门系统与抗反流屏障。图1a:门系统的结构组成;图1b:门框结构;图1c:把手系统;图1d:抗反流屏障的结构组成;图1e:"coincide"结构;图1f:抗反流瓣复合体
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