Through monitoring esophageal dynamic change, detection of laryngopharyngeal reflux and gastroesophageal reflux events, to discuss the relationship of OSAHS with laryngopharyngeal reflux.

Thirty patients with OSAHS were diagnosed by polysomnography in the Xinjiang autonomous region people′s hospital between February 2013 and June 2014. This study applied high-resolution esophageal manometry and ambulatory 24-hour multichannel intraluminal impedance-pH monitoring to obtain the upper esophageal sphincter pressure and lower esophageal sphincter pressure, characteristics of sectional esophageal motility; laryngopharyngeal reflux and gastroesophageal reflux events, as well as the reflux properties of substance. Ten healthy persons were recruited as normal controls.

UES relaxation duration, duration of UES relaxtion time, UES relaxtion recovery time and mean length of LES were all shorter than those of the control group (t were -2.061, -2.044, -2.525, -2.076 and 2.522, P<0.05). Median scores of Demeester were11.3[5.1; 37.8] and 3.8[2.8; 11.1] in OSAHS group and the controls, median frequency of total reflux episodes were 41.5[23.8; 65.3] and 24.5[16.3; 27.8]. The frequency of total reflux episodes, time of acid clearance, Demeester scores were increased or higher in OSAHS group than those in the controls(z were -2.438, -2.361 and -2.140, P<0.05).

There are upper esophageal sphincter and lower esophageal sphincter dismotility in OSAHS patients. Esophageal dynamic disfunction should be considered in the study of the pathogenesis of OSAHS.