To investigate the effect of laparoscopic ventilation on respiratory function in patients with esophageal hiatal hernia and GERD under laparoscopy.

A prospective study was conducted in Department of Anesthesiology, Xinjiang Uygur Autonomous region including 80 cases of patients who had undergone laparoscopic esophageal hiatal hernia repair from April 2014 to October 2017 were selected and divided into control group and observation group.In the control group, the traditional capacity control ventilation mode was adopted and the tidal volume was set at 10 ml/kg according to the patient with weight.Breathing rate is set to 12 times per minute.In the observation group, the lung ventilation strategy was adopted.The tidal volume was set to 6 ml/kg according to the patient with weight and 5 cm H₂O positive end-pressure ventilation.The mean arterial pressure(MAP)and central venous pressure(CVP)of the two groups were recorded before pneumoperitoneum(T₀), 2 h after pneumoperitoneum(T₁)and 4 h after pneumoperitoneum(T₂)respectively.Lung compliance(C), heart rate(HR)and respiratory rate(RR)were recorded at T₀, T₁, T₂ and 24 hours after surgery(T₃). Blood gas was drawn and oxygenation index(OI)was calculated.

Higher levels of MAP, CVP and C were found among T₁ and T₂ than T₀, both in the control and observation group(all P<0.05), so the same as HR, RR and OI.In addition, higher level of C was found in the observation group than the control group at T₀, T₁ and T₂, respectively(all P<0.05), but not for MAP and CVP.

Compared with the traditional volume control ventilation mode, pulmonary protective ventilation strategy can improve respiratory function of patients with laparoscopic treatment of esophageal hiatal hernia and GERD.