Different methods of treatment of 206 cases of Barrett′s esophagus observation of efficacy

doi:10.3877/cma.j.issn.1674-6899.2017.02.005

Abstract

Abstract:

Objective

To investigate the efficacy of Argon plasma coagulation(APC)combined with esomeprazole enteric-coated tablets in the treatment of Barrett′s esophagus.

Methods

The clinical data of 284 patients with endoscopy and diagnosed BE were analyzed retrospectively from January 2015 to January 2016 in Xinjiang Uygur AutonomousRegion People′s Hospital.Among them, 78 patients were treated with estradiol enteric(group A); 206 patients underwent APC combined with estradiol enteric-coated tablets(group B). Compared the clinical efficacy between the two groups before and after treatment.

Results

The BE mucosa of group A was not significantly reduced while it was disappeared in 97.57% patients in group B.

Conclusion

APC combined with esomeprazole enteric-coated tablets is a simple, safe and reliable method for the treatment of esophageal mucosa in patients with BE lesions.It can not only improve the symptoms of BE, but also can cure the BE lesions, which is worthy of clinical application.

Key words: Barrett esophagus, Argon plasma coagulation, Proton pump inhibition, Treatment outcome

Xiaolei He, Xiaoling Huang, Feng Gao. Different methods of treatment of 206 cases of Barrett′s esophagus observation of efficacy[J]. Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition), 2017, 04(02): 63-65.

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一般情况	例数	男[例(%)]	女[例(%)]	平均年龄(岁，±s)	胸骨后不适[例(%)]	烧心及反流[例(%)]	上腹部不适[例(%)]
A组	78	43(55.13)	35(44.87)	60.24±4.30	30(38.46)	25(32.10)	23(29.49)
B组	206	125(60.68)	81(39.32)	58.86±7.62	91(44.17)	69(33.50)	46(22.33)
检验值	?	χ²＝0.015		t＝3.139	χ²＝2.745	χ²＝3.668	χ²＝2.231
P值	?	0.902		0.090	0.103	0.070	0.115

一般情况	例数	男[例(%)]	女[例(%)]	平均年龄(岁，±s)	胸骨后不适[例(%)]	烧心及反流[例(%)]	上腹部不适[例(%)]
A组	78	43(55.13)	35(44.87)	60.24±4.30	30(38.46)	25(32.10)	23(29.49)
B组	206	125(60.68)	81(39.32)	58.86±7.62	91(44.17)	69(33.50)	46(22.33)
检验值	?	χ²＝0.015		t＝3.139	χ²＝2.745	χ²＝3.668	χ²＝2.231
P值	?	0.902		0.090	0.103	0.070	0.115

	例数	胃镜下黏膜改变类型
	例数	岛型	舌型	全周型
A组	78	2(2.56)	3(3.85)	0(0)
B组	206	98(47.57)^#	74(35.92)^#	29(14.08)^#

	例数	胃镜下黏膜改变类型
	例数	岛型	舌型	全周型
A组	78	2(2.56)	3(3.85)	0(0)
B组	206	98(47.57)^#	74(35.92)^#	29(14.08)^#

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