To investigate the effect of gastroesophageal anastomosis combined with Nissen fundoplication on postoperative gastroesophageal reflux in esophageal cancer operation patients.

A retrospective analysis from September 2015 to March 2017 in the people's Hospital of Xinjiang Uygur Autonomous Region who parallel resection in 31 cases of esophageal cancer patients, according to the operation mode divided into two groups, the observation group received esophagogastric anastomosis combined with Nissen fundoplication (15 cases), the control group received non fundoplication whole stomach esophagus anastomosis (16 cases), after the surgery until the patient to return to normal gastrointestinal function uses dynamic monitor its pH 24 h esophageal pH monitoring chamber, the other respectively after 1, 3, 6, 12 month using GerdQ and compared with two groups of patients postoperative gastroesophageal reflux.

There were no deaths occurred, and no occurrence of postoperative anastomotic fistula and thoracic gastric emptying dysfunction, etc; 24 hours reflux episodes long Nissen fundoplication group and significalldy less than the number Of non fundoplication whole stomach esophagus anastomosis, the longest duration of reflux and pH value<4.00 The cumulative time was significantly shorter in non fundoplication whole stomach esophagus anastomosis, DeMeester scores were significantly lower than the non fundoplication whole stomach esophagus anastomosis group, between groups were statistically significant (P<0.05), and after 1、3、6、12 month later the gastric reflux disease questionnaire (GerdQ) score was significantly lower than the non fundoplication whole stomach esophagus anastomosis group (P<0.05).

esophagogastric anastomosis combined with Nissen fundoplication compared with conventional non fundoplication whole stomach esophagus anastomosis resection Of esophageal cancer has a more ideal GER disease controleffect, and can provide a reference for the choice of nastomosis ways for patientswith esophageal cancer surgery.