Meta analysis of therapeutic effect of peroral endoscopic cardial constriction on reflux esophagitis

doi:10.3877/cma.j.issn.2095-8765.2022.01.001

Abstract

Abstract:

Objective

To systematically evaluate the therapeutic effect of peroral endoscopic cardial constriction (PECC) on reflux esophagitis (RE).

Methods

We searched the randomized controlled trial (RCT) studies of PECC in the treatment of RE from January 1, 2013 to March 10, 2022 in databases of CNKI, VIP, Wanfang Data knowledge service platform, China biomedicine, the Cochrane Library, Ovid, PubMed and EMBASE by computer. Data extraction and quality evaluation were conducted for the literatures that met the inclusion criteria. We used Revman 5.4 software to perform meta-analysis on the data.

Results

This meta-analysis included in 5 articles and a total of 352 patients. Results of meta-analysis showed that the effective rate of RE in PECC group was higher than that in proton pump inhibitor (PPI) control group (OR=5.55,95%CI:1.90-16.22), and the recurrence rate was lower than that in control group (OR=0.11,95%CI:0.04-0.35).

Conclusion

PECC has a good clinical therapeutic effect on RE. The literatures and studies included in this meta-analysis are few, so we need to collect more relevant studies for verification in the future.

Key words: Reflux esophagitis, Peroral endoscopic cardial constriction, Meta-analysis

Xiaolin Wang, Changzheng Li, Tian Tian, Jing Xie, Ningbo Hao, Wenwei Hu, Xue Li, Dan Zhang. Meta analysis of therapeutic effect of peroral endoscopic cardial constriction on reflux esophagitis[J]. Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition), 2022, 09(01): 1-5.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhwsgflbdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-8765.2022.01.001

https://zhwsgflbdzzz.cma-cmc.com.cn/EN/Y2022/V09/I01/1

Figures/Tables 7

References 12

1	Savarino E, Marabotto E, Bodini G, et al. Epidemiology and natural history of gastroesophageal reflux disease[J]. Minerva Gastroenterol Dietol, 2017, 63(3):175-183.
2	王潇潇, 令狐恩强, 王宇菲. 内镜下贲门缩窄术治疗胃食管反流病的报道一例[J/OL]. 中华腔镜外科杂志(电子版), 2013, 6(6):468-469.
3	Heijkoop B, Parker N, Kiroff G, et al. Effectiveness and safety of inpatient versus extended venous thromboembolism (VTE) prophylaxis with heparin following major pelvic surgery for malignancy: protocol for a systematic review[J]. Syst Rev, 2019, 8(1):249.
4	冯欣宇. 内镜下行贲门黏膜套扎缩窄术治疗反流性食管炎的临床价值研究[J]. 健康女性, 2021(4):66.
5	张莉. 反流性食管炎患者开展内镜下行贲门黏膜套扎缩窄术治疗的效果分析[J]. 健康必读, 2021(6):255.
6	史芳芳,散红霞. 内镜下贲门黏膜套扎缩窄术在反流性食管炎治疗中的应用价值及可行性分析[J]. 特别健康, 2021(33):23.
7	曹会霞, 熊英, 韩静, 等. 经口内镜下贲门缩窄术和双倍剂量艾司奥美拉唑治疗难治性胃食管反流病的临床疗效对比[J/OL]. 中华胃肠内镜电子杂志, 2021, 8(4):171-175.
8	唐帅, 兰伟平, 唐小华, 等. 内镜下行贲门黏膜套扎缩窄术治疗反流性食管炎的临床价值研究[J]. 中国医学创新, 2020, 17(22):33-36.
9	中国医师协会消化医师分会胃食管反流病专业委员会, 中华医学会消化内镜学分会食管疾病协作组. 2020年中国胃食管反流病内镜治疗专家共识[J]. 中华消化内镜杂志, 2021, 38(1):1-12.
10	张熠. 内镜下贲门缩窄术与腹腔镜Nissen胃底折叠术治疗胃食管反流病的效果对比[D]. 河南大学, 2020.
11	郑研艳. 抗反流黏膜切除术和贲门缩窄术治疗胃食管反流病的临床疗效对比[D]. 郑州大学, 2020.
12	常越, 陈希, 田永, 等. 应用内镜下贲门部套扎紧缩成形术治疗胃食管反流病的临床疗效[J]. 中国内镜杂志, 2020, 26(9): 19-24.

第一作者	发表时间（年份）	国家	例数（T/C）	干预措施（T/C）	疗程（周）	结局指标
Cao Huixia	2021	中国	32/32	PECC/PPI	3、6个月	RDQ、RSI、GERD-HRQL评分
Zhang Li	2021	中国	32/32	PECC/PPI	1个月	有效率、复发率
San Hongxia	2021	中国	47/47	PECC/PPI	1、5个月	食管pH、食管压力、COX-2、E-cadherin、复发率
Feng Xinyu	2021	中国	35/35	PECC/PPI	3个月	有效率、复发率
Tang shuai	2020	中国	30/30	PECC/PPI	1、3个月	食管pH、食管压力、GERD-HRQL评分、COX-2、E-cadherin、病理学积分

第一作者	发表时间（年份）	国家	例数（T/C）	干预措施（T/C）	疗程（周）	结局指标
Cao Huixia	2021	中国	32/32	PECC/PPI	3、6个月	RDQ、RSI、GERD-HRQL评分
Zhang Li	2021	中国	32/32	PECC/PPI	1个月	有效率、复发率
San Hongxia	2021	中国	47/47	PECC/PPI	1、5个月	食管pH、食管压力、COX-2、E-cadherin、复发率
Feng Xinyu	2021	中国	35/35	PECC/PPI	3个月	有效率、复发率
Tang shuai	2020	中国	30/30	PECC/PPI	1、3个月	食管pH、食管压力、GERD-HRQL评分、COX-2、E-cadherin、病理学积分

[1]	Siping Zhang, Wei Liu, Pengcheng Ma. Therapeutic effects of lower extremity mild varus alignment after total knee arthroplasty [J]. Chinese Journal of Joint Surgery(Electronic Edition), 2023, 17(06): 808-817.
[2]	Wanglin Luo, Chuanjun Yang, Guoxing Xu, Jianguo Yu, Weidong Sun, Wenjuan Yan, Zhi Feng. Meta analysis on implantation of different grafting materials in open wedge high tibial osteotomy [J]. Chinese Journal of Joint Surgery(Electronic Edition), 2023, 17(06): 818-826.
[3]	Hongxing Chen, Lijun Zhang, Yong Zhang, Hu Li, Chi Zhou, Yinuo Fan. Meta-analysis of effect of external application of traditional Chinese medicine after arthroscopic debridement in knee osteoarthritis [J]. Chinese Journal of Joint Surgery(Electronic Edition), 2023, 17(05): 663-672.
[4]	Yang Xing, Aishan He, Yan Kang, Zibo Yang, Fangang Meng, Peihui Wu. Meta-analysis of single-bundle reconstruction combining anterolateral reconstruction of anterior cruciate ligament [J]. Chinese Journal of Joint Surgery(Electronic Edition), 2023, 17(04): 508-519.
[5]	Zhudan Yin, Yu Wang, Ke Zhen, Bin Xu, Yali Tian, Zirong Tong. Effect of early hypocaloric enteral nutrition support on prognosis in critically ill patients: a meta-analysis [J]. Chinese Journal of Critical Care Medicine(Electronic Edition), 2023, 16(03): 215-222.
[6]	Wei Yang, Xia Hao, Dongzhen Zhu, Jinbo Zhang, Xuefei Tian, Bin Yao. A meta analysis of the clinical effect of traditional Chinese medicine on burn and scald patients [J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2023, 18(05): 419-426.
[7]	Xiongxiong Li, Chan Zhou, Ting Xu, Yu Ren, Jin Shang. Metastasis rate of newly diagnosed ductal carcinoma in situ with microinvasive axillary lymph nodes: A Meta-analysis [J]. Chinese Archives of General Surgery(Electronic Edition), 2023, 17(06): 466-474.
[8]	Zaibo Zhang, Bingyu Wang, Zhikai Jiao, Bibo Tan. Risk factors for lower extremity deep venous thrombosis after gastric cancer surgery: A Meta-analysis [J]. Chinese Archives of General Surgery(Electronic Edition), 2023, 17(06): 475-480.
[9]	Huiming Wu, Renkai Guo, Huiyu Li. Safety and efficacy of robot-assisted natural orifice specimen extraction surgery for colorectal cancer: A meta-analysis [J]. Chinese Archives of General Surgery(Electronic Edition), 2023, 17(05): 395-400.
[10]	Xian Mo, Chuang Yang. Meta-analysis of risk factors for portal vein thrombosis in patients with cirrhosis [J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2023, 17(06): 678-683.
[11]	Wenzhong Duan, Yanxia Bai, Wenting Xu, Hongxia Qi, Zhijian Lyu. Anesthetic effects of sevoflurane and propofol in hepatectomy: a Meta-analysis [J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2023, 12(06): 640-645.
[12]	Hailong Yang, Manjun Deng, Yichen Fan, Mengyu Xu, Fangde Chen, Weihao Wu, Shengyuan Zhang. Risk factors of bile leakage after primary suture of laparoscopic common bile duct exploration: a Meta-analysis [J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2023, 12(05): 545-550.
[13]	Hongli Xu, Yulin Yang, Qing Xue, Qian Zhang, Lihong Ma, Zhengang Qiu. Efficacy of extracorporeal shock wave for non-specific low back pain: a systematic review and Meta-analysis [J]. Chinese Journal of Geriatric Orthopaedics and Rehabilitation(Electronic Edition), 2023, 09(05): 307-314.
[14]	Xiu Wang, Yiguo Wang. Efficacy and safety of ustekinumab in treating perianal fistulizing Crohn′s disease: a meta-analysis [J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2023, 13(06): 514-519.
[15]	Huiyuan Su, Hongtao Song, Wei Gao, Zhong Wu. Acupuncture for treatment of simple obesity: systematic review and Meta-analysis [J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2023, 12(03): 123-128.

Please choose a citation manager

Content to export