Advancements in the diagnosis and treatment of gastroesophageal reflux disease with esophageal dysmotility

doi:10.3877/cma.j.issn.1672-6448.2024.03.007

Abstract

Abstract:

Gastroesophageal reflux with esophageal dysmotility is a low-incidence digestive system disease. The pathogenesis is currently unclear.High-resolution manometry is the preferred method for diagnosing gastroesophageal reflux disease （GERD） and esophageal dysmotility （ED）. Other diagnostic methods include endoscopy and barium swallow imaging of the esophagus.In clinical practice, GERD and ED can be classified as primary and secondary. In primary cases, achalasia is a relatively common condition,while in secondary diseases, systemic sclerosis is more prevalent.Treatment for GERD and ED includes conservative and surgical options. Conservative treatment methods include endoscopic botulinum toxin injection and the use of 5-HT receptor agonists.Surgical treatment adopts different methods for primary and secondary GERD with ED. Primary GERD typically includes procedures such as pneumatic dilation,laparoscopic Heller myotomy, and peroral endoscopic myotomy.For secondary GERD and ED, common surgical methods include laparoscopic fundoplication, Roux-en-Y gastric bypass surgery, electrical stimulation therapy,and laparoscopic magnetic sphincter augmentation.This review aims to explore the progress in the diagnosis and treatment of GERD and ED, providing references and guidance for clinical practice and future research.

Key words: Gastroesophageal reflux disease, Esophageal Dysmotility, High Resolution Manometry, Conservative treatment, Surgical treatment

Hu Liu, Zhen Ren, Xiaohan Wei, Chen Pan, Lisheng Wu. Advancements in the diagnosis and treatment of gastroesophageal reflux disease with esophageal dysmotility[J]. Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition), 2024, 11(03): 153-158.

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