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Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition) ›› 2015, Vol. 02 ›› Issue (03): 131-134. doi: 10.3877/cma.j.issn.1674-6899.2015.03.002

Special Issue:

• Original Article • Previous Articles     Next Articles

Comparative study on condition of gastroesophageal reflux disease after two types of surgeries for Siewert Ⅱ/Ⅲ type gastroesophageal junction adenocarcinoma

Bing Qu1, Bin Ren2, Bingsong Lei3, Hong Yan1, Hui Hu1,(), Zhi Zhang1   

  1. 1. Department of General Surgery, Affiliated Hua Run General Hospital of Wuhan Steel Company, Wuhan 430080, China
    2. Department of Clinical Laboratory, Eighth Hospital of Wuhan, Wuhan 430080, China
    3. Department of Clinical Laboratory, Affiliated Hua Run General Hospital of Wuhan Steel Company, Wuhan 430080, China
  • Received:2015-02-23 Online:2015-08-15 Published:2015-08-15
  • Contact: Hui Hu
  • About author:
    Corresponding author: Hu Hui, Email:

Abstract:

Objective

To compare the condition of gastroesophageal reflux disease(GERD) after two types of surgeries for Siewert Ⅱ/Ⅲ type gastroesophageal junction adenocarcinoma.

Methods

From January 2013 to December 2014, patients in Affilated Hua Run General Hospital of Wuhan Steal Company, diagnosed as Siewert Ⅱ/Ⅲ type AEG were randomly divided into two groups. Group A, laparoscopic resection of the proximal part of the stomach + esophagus residual anastomosis + pyloroplasty; group B, laparoscopic gastrectomy + esophagus jejunum Roux-en-Y surgery, by monitoring gastrointestinal drainage volume, esophageal pH value, burning pain under sternum, bile vomiting, weight loss and a series of clinical symptoms, two groups of patients with reflux esophagitis were compared.

Results

Postoperative gastrointestinal drainage was significantly lower in group B than in group A (P<0.05), the total amount of time for postoperative esophageal pH<4 was less in group B than in group A (P<0.05). One week after surgery, postoperative epigastric burning pain, weight loss compared with preoperative condition, bilious vomiting, and reflux esophagitis incidence in group B were significantly lower than in group A (9.1% vs.63.6%, P<0.05) .

Conclusion

Group B is superior to group A in gastrointestinal drainage volume, esophageal pH value, and the incidence of adverse reactions.

Key words: SiewertⅡ/Ⅲtype, Gastroesophageal junction adenocarcinoma, Gastroesophageal reflux disease

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