Effect of two different total gastrectomy on postoperative reflux esophagitis in patients with upper or middle gastric cancer

doi:10.3877/cma.j.issn.2095-8765.2018.03.002

Abstract

Abstract:

Objective

To investigate the effect of total gastrectomy Roux-en-Y anastomosis and total gastrectomy Stacked anastomosis and Braun's anastomosis on reflux esophagitis by comparing two different total gastrectomy.

Methods

The clinical data of total gastrectomy in 80 patients with gastric cancer admitted to People's Hospital of Xinjiang Uyghur Autonomous Region from August 2015 to January 2017 were retrospectively analyzed. The incidence of reflux esophagitis within one year after follow-up was retrospectively analyzed.

Results

The rate of reflux esophagitis was 14.3% in the total gastrectomy Roux-en-Y anastomosis group, which was significantly higher than that of Stacked anastomosis and Braun's anastomosis (55.3%) due to total gastrectomy (χ²=7.372, P<0.05).

Conclusion

Total gastrectomy of Roux-en-Y anastomosis maybe reduce the possible of postoperative reflux esophagitis.

Key words: Gastric cancer, Total gastrectomy, Esophagitis, Reflux

Peng Li, Li Tao, Nuermaimaiti Sikandeer·. Effect of two different total gastrectomy on postoperative reflux esophagitis in patients with upper or middle gastric cancer[J]. Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition), 2018, 05(03): 102-104.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhwsgflbdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-8765.2018.03.002

https://zhwsgflbdzzz.cma-cmc.com.cn/EN/Y2018/V05/I03/102

Figures/Tables 1

References 12

[1]	Rieder F, Biancani P, Harnett K, et al. Inflammatory mediators in gastroesophageal reflux disease: impact on esophageal motility, fibrosis, andcarcinogenesis[J]. Am J Physiol Gastrointest Liver Physiol, 2010, 298(5):G571-581.
[2]	Ferlay J, Soerjomataram I, Dikshit R, et al. Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN2012[J]. Int J Cancer, 2015, 136, E359-E386.
[3]	Torre LA, Siegel RL, Ward EM, et al. Global Cancer Incidence and Mortality Rates and Trends-An Update[J]. Cancer Epidemiol Biomark Prev, 2016, 25, 16-27.
[4]	Plummer M, Franceschi S, Vignat J, et al. Global burden of gastric cancer attributable to Helicobacter pylori[J]. Int J Cancer, 2015, 136, 487-490.
[5]	Van Cutsem E, Sagaert X, Topal B, et al. Gastric cancer Lancet, 2016, 388, 2654-2664.
[6]	马君俊，臧潞，胡伟国，等．全腹腔镜远端胃癌根治术胃空肠非离断式Roux-en-Y吻合51例疗效分析[J]．中国实用外科杂志, 2016, 36(9):965-967
[7]	Badillo R, Francis D. Diagnosis and treatment of gastroesophageal reflux disease[J]. World J Gastrointest Pharmacol Ther, 2014, 5(3):105-112.
[8]	El-Serag HB, Sweet S, Winchester CC, et al. Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review.[J] Gut, 2014, 63(6):871-880.
[9]	Kang JW, Lee SM. Protective effects of chlorogenic acid against experimental reflux esophagitis in rats[J]. Biomol Ther (Seoul), 2014, 22(5):420-425.
[10]	克力木·阿不都热依木，吾布力卡斯木·吾拉木．腹部放射学协会(SAR）注重疾病小组共识声明：食管钡餐造影在胃食管反流病中的作用[J/CD]．中华胃反流病电子杂志, 2017, 4(1):1-6.
[11]	薛令凯，崔庆，赵强，等．近端胃癌2种手术方式术后发生反流性食管炎的对比研究[J]．中国现代普通外科进展, 2017, 20(7):546-548.
[12]	臧潞，马君俊.全腹腔镜胃癌根治术消化道重建及相关并发症处理[J].中国使用外科杂志, 2017, 37(4):369-373.

?		例数	试验组（42例）	对照组（38例）	χ²值	P值
性别		?	?	?	0.067	0.210
?	男性	43	22	21	?	?
?	女性	37	20	17	?	?
年龄		?	?	?	1.042	0.181
?	≥60岁	41	21	20	?	?
?	<60岁	39	21	18	?	?
肿瘤分期		?	?	?	0.115	0.734
?	ⅡIIA期	12	6	6	?	?
?	ⅡIIB期	21	12	9	?	?
?	ⅢIIIA期	32	18	14	?	?
?	ⅢIIIB期	9	3	6	?	?
?	ⅢIIIC期	6	3	3	?	?
细胞分化程度		?	?	?	0.208	0.836
?	高分化	12	7	5	?	?
?	中分化	45	22	23	?	?
?	低分化	20	12	8	?	?
?	未分化	3	1	2	?	?
反流性食管炎		?	?	?	7.372	0.007^a
?	有	27	6	21	?	?
?	无	53	36	17	?	?
Visick分级		?	?	?	0.172	0.678
?	ⅠI级	53	36	17	?	?
?	ⅡII级	6	2	4	?	?
?	ⅢIII级	12	3	9	?	?
?	ⅣIV级	9	1	8	?	?
胃镜Savary-Miller分级		?	?	?	0.464	0.496
?	ⅠI级	12	4	8	?	?
?	ⅡII级	7	1	6	?	?
?	ⅢIII级	0	0	0	?	?
?	ⅣIV级	0	0	0	?	?

?		例数	试验组（42例）	对照组（38例）	χ²值	P值
性别		?	?	?	0.067	0.210
?	男性	43	22	21	?	?
?	女性	37	20	17	?	?
年龄		?	?	?	1.042	0.181
?	≥60岁	41	21	20	?	?
?	<60岁	39	21	18	?	?
肿瘤分期		?	?	?	0.115	0.734
?	ⅡIIA期	12	6	6	?	?
?	ⅡIIB期	21	12	9	?	?
?	ⅢIIIA期	32	18	14	?	?
?	ⅢIIIB期	9	3	6	?	?
?	ⅢIIIC期	6	3	3	?	?
细胞分化程度		?	?	?	0.208	0.836
?	高分化	12	7	5	?	?
?	中分化	45	22	23	?	?
?	低分化	20	12	8	?	?
?	未分化	3	1	2	?	?
反流性食管炎		?	?	?	7.372	0.007^a
?	有	27	6	21	?	?
?	无	53	36	17	?	?
Visick分级		?	?	?	0.172	0.678
?	ⅠI级	53	36	17	?	?
?	ⅡII级	6	2	4	?	?
?	ⅢIII级	12	3	9	?	?
?	ⅣIV级	9	1	8	?	?
胃镜Savary-Miller分级		?	?	?	0.464	0.496
?	ⅠI级	12	4	8	?	?
?	ⅡII级	7	1	6	?	?
?	ⅢIII级	0	0	0	?	?
?	ⅣIV级	0	0	0	?	?

[1]	Guoxin Li, Xinhua Chen. Progress of clinical research on esophagojejunal anastomosis after total laparoscopic gastrectomy [J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2025, 19(01): 1-4.
[2]	Fangpeng Chen, Dawei Yang, Congwen Jin. Effect of laparoscopic proximal gastrectomy combined with modified esophagogastrostomy to reconstruct His Angle in patients with postoperative reflux esophagitis [J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2025, 19(01): 15-18.
[3]	Lang Bai, Xueyu Zhang, Tiecheng Bai, Aijun He. Effect of conical overlapping anastomoplasty during laparoscopic proximal gastrectomy on gastroesophageal reflux and nutritional status in Siewert type II AEG patients [J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2024, 18(06): 679-682.
[4]	Haiyun Li, Minxian Zhao, Yingmo Shen, Huiqi Yang. Research progress of fundoplication in preventing postoperative complications of hiatal hernia [J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2024, 18(05): 485-490.
[5]	Qi Han, Maimaitiming Maimaitiaili, Xudong Huang, Hao Wang, Abudureyimu Kelimu, Aili Aikebaier. Mid-term efficacy analysis of laparoscopic sleeve gastrectomy or combined with hiatal hernia repair in the treatment of obesity with gastroesophageal reflux disease [J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2024, 18(05): 501-506.
[6]	Chuanfu Ren, Zhi Yang, En Xu, Ziyun He, Banxin Luo, Xin Chen, Xuefeng Xia. Laparoscopic hernia repair with fundoplication for hiatal hernia with gastroesophageal reflux disease:A clinical analysis of 40 patients [J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2024, 18(05): 507-511.
[7]	Chenyang Du, Yong Wang, Xin Duan, Wenjie Ke, Nian Shi, Yingxiang Wu, Wen Luo. Analysis of risk factors for dysphagia after laparoscopic hiatal hernia repair [J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2024, 18(05): 523-527.
[8]	Peng Wang, Xinxin Shao, Haitao Hu, Yantao Tian, Yuxin Zhong. Application of modified MOBS anastomosis in total laparoscopic proximal gastrectomy [J]. Chinese Journal of Laparoscopic Surgery(Electronic Edition), 2024, 17(05): 267-270.
[9]	Haitao Hu, Xinxin Shao, Yujuan Jiang, Peng Wang, Weikun Li, Yiming Lu, Yantao Tian. The impact of duodenal stump management on postoperative complications following totally laparoscopic gastrectomy for gastric cancer [J]. Chinese Journal of Laparoscopic Surgery(Electronic Edition), 2024, 17(04): 205-209.
[10]	Zeqin Wang, Jun Hong, Yaping Wang, Jian Wang, Hankun Hao. The application of W-shaped liver suspension technique in totally laparoscopic total gastrectomy [J]. Chinese Journal of Laparoscopic Surgery(Electronic Edition), 2024, 17(04): 218-221.
[11]	Zhiwei Hu, Jimin Wu, Changrong Deng, Xiulan Zhan, Tao Ji, Feng Wang, Shurui Tian, Dong Chen, Yu Zhang, Jiannan Liu, Qing Song. Anti reflux mucosal ligation for the treatment of refractory gastroesophageal reflux disease [J]. Chinese Journal of Laparoscopic Surgery(Electronic Edition), 2024, 17(04): 227-233.
[12]	Xianyong Liu, Dongmei Qin, Ruomei Zhang, Junjiao Li, Chunqin Meng, Mingxin Wu, Yuhong Wang, Xinxian Zhao, Ruilian Xv, Wenwen Hong, Ling Ma, Wei Qiu, Yu Zhou. Expression and significance of Her2/Hes1 in three pathological stages of Correa cascade in intestinal gastric cancer [J]. Chinese Journal of Cell and Stem Cell(Electronic Edition), 2024, 14(06): 321-327.
[13]	Xi Gan, Xin Liao. Correlation analysis of tumor deposition near gastric cancer with CT imaging characteristics, serum indexes and pathological characteristics [J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2024, 14(05): 422-425.
[14]	Xiaojiu Tang, Man Hu, Bijun Xu, Ya Xiao. Study on the correlation between the severity of obesity combined with gastroesophageal reflux disease patients and their anxiety, depression and nutritional status [J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2024, 14(04): 360-364.
[15]	Lihui Wang, Haitao Du, Jun Wan, Qianqian Chen. Clinical application of dynamic reflux monitoring in the diagnosis of esophageal-laryngopharyngeal reflux diseases [J]. Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition), 2024, 11(04): 268-272.

Please choose a citation manager

Content to export