Comqarison on the consumption of propofol with laparoscopic esophageal hiatal hernia repair between patients of Uygur and Han nationalities

doi:10.3877/cma.j.issn.2095-8765.2019.03.008

Abstract

Abstract:

Objective

To comqarison of the consumption of propofol with Laparoscopic Esophageal Hiatal Hernia Repair between patients of Uygur and Han nationalities.within scopes of the basic value plus or minus 20%.The consumption of propofol bispectral index (BIS),mean arterial pressure(MAP) and heart rate (HR) values at just at the anesthesia induction(T₀), pneumoperitoneum(T₁), 1~20 min after pneumoperitoneum(T₂), 21~40 min after pneumoperitoneum (T₃), 41~60 min after pneumoperitoneum(T₄), 61~80 min after pneumoperitoneum(T₅), 81~100 min after pneumoperitoneum(T₆), 101~120 min after pneumoperitoneum(T₇); 121~1400 min after pneumoperitoneum(T₈), 141 min after pneumoperitoneum to stopping pneumoperitoneum(T₉) of the two groups were observed and recorded．

Results

The consumption of propofol at T₀ time segments no statistical difference between the two groups(P＞0.05); At T₁~T₉ time segments, the consumption of propofol in the Uygur group were significantly higher than those in the Han group(P＜0.05); The MAP and HR at T₁~T₉ time segments no statistical difference between the two groups (P＞0.05).

Conclusions

The consumption of propofol in Han nationalities is higher to that in Uighurs, which may through Genetic polymorphism of metabolic enzyme gene.

Key words: Laparoscopic Esophageal Hiatal Hernia Repair, Uygur nationalities, Han nationalities, propofol

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Figures/Tables 2

References 16

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丙泊酚用量	维吾尔族组（n=22）	汉族组（n=21）	t	P
T₀	410.27±6.41	408.38±7.41	0.895	＞0.05
T₁	177.13±5.61	164.50±5.28	7.594	＜0.05
T₂	204.97±7.12	191.32±6.99	6.340	＜0.05
T₃	207.87±6.47	190.10±6.37	9.070	＜0.05
T₄	206.09±5.64	191.98±5.15	8.554	＜0.05
T₅	206.05±5.32	190.80±6.18	8.684	＜0.05
T₆	205.17±5.75	189.54±5.95	8.760	＜0.05
T₇	205.80±6.13	191.27±4.21	9.017	＜0.05
T₈	206.44±6.95	192.94±4.96	7.300	＜0.05
T₉	317.23±10.85	264.03±9.22	17.286	＜0.05
丙泊酚总用量	2370.70±23.94	2219.38±19.81	22.522	＜0.05

丙泊酚用量	维吾尔族组（n=22）	汉族组（n=21）	t	P
T₀	410.27±6.41	408.38±7.41	0.895	＞0.05
T₁	177.13±5.61	164.50±5.28	7.594	＜0.05
T₂	204.97±7.12	191.32±6.99	6.340	＜0.05
T₃	207.87±6.47	190.10±6.37	9.070	＜0.05
T₄	206.09±5.64	191.98±5.15	8.554	＜0.05
T₅	206.05±5.32	190.80±6.18	8.684	＜0.05
T₆	205.17±5.75	189.54±5.95	8.760	＜0.05
T₇	205.80±6.13	191.27±4.21	9.017	＜0.05
T₈	206.44±6.95	192.94±4.96	7.300	＜0.05
T₉	317.23±10.85	264.03±9.22	17.286	＜0.05
丙泊酚总用量	2370.70±23.94	2219.38±19.81	22.522	＜0.05

组别	BIS	MAP（mmHg）	HR（次/min）
维吾尔族组（n=22）	44.16±4.81	96.47±5.83	78.46±6.55
汉族组（n=21）	44.34±4.28	96.76±5.70	77.69±6.79
t	0.129	0.164	0.378
P	＞0.05	＞0.05	＞0.05

组别	BIS	MAP（mmHg）	HR（次/min）
维吾尔族组（n=22）	44.16±4.81	96.47±5.83	78.46±6.55
汉族组（n=21）	44.34±4.28	96.76±5.70	77.69±6.79
t	0.129	0.164	0.378
P	＞0.05	＞0.05	＞0.05

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