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Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition) ›› 2023, Vol. 10 ›› Issue (03): 156-159. doi: 10.3877/cma.j.issn.2095-8765.2023.03.010

• Review • Previous Articles     Next Articles

Study on the correlation between gastroesophageal reflux disease and the pathogenesis of capsaicin receptor

Yakufu Sulayiman·1, Yiliang Li2,(), Abudureyim Kelim·2   

  1. 1. Department of Minimally Invasive Surgery, Hernia and Abdominal Wall Surgery, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China,
    2. Department of Minimally Invasive Surgery, Hernia and Abdominal Wall Surgery, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China,;Research Institute of General and Minimally Invasive Surgery, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China
  • Received:2023-02-21 Online:2023-08-15 Published:2024-03-21
  • Contact: Yiliang Li

Abstract:

Gastroesophageal reflux disease (GERD) is a common gastrointestinal motility disorder caused by the reflux of gastric contents into the straight esophagus or oral cavity. At present, the incidence rate of this disease is on the rise worldwide. So far, people's understanding of the pathogenesis of gastroesophageal reflux has mainly focused on in-depth exploration and research on the mechanism of reflux. But in recent years, molecular mechanisms have gradually become a research hotspot. This review focuses on the role of capsaicin receptor in the pathogenesis of GERD.

Key words: Gastroesophageal reflux diseas, Vanill oid receptor subtype 1, Gas accommodation, Glial-derived neurotrophic factor

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