To explore the risk factors of bronchial asthma combined with gastroesophageal reflux disease (GERD), and to provide theoretical basis for prevention and treatment.

The clinical data of 187 cases of bronchial asthma with GERD and 192 cases of bronchial asthma with GERD were collected retrospectively from January 2013 to August 2018 in the respiratory department of the people's Hospital of Xinjiang Uygur Autonomous Region.

There were no significant difference in age, gender, history of allergy, history of hypertension, history of coronary heart disease, history of diabetes mellitus and history of drinking between the two groups (P＞0.05); there were significant differences in smoking history, body mass index (BMI), family history of asthma, forced expiratory volume in one second (FEV1), FEV1 /forced vital capacity (FVC), peak expiratory flow (PEF) and the number of acute attacks in the past 12 months between the two groups (P＜0.05); Multivariate logistic regression analysis showed that high BMI, smoking, PEF and the number of previous acute attacks in 12 months were independent risk factors for asthma complicated with GERD (P＜0.05).

The high BMI, smoking, PEF and the number of acute attacks in the past 12 months are the risk factors of GERD, it is expected to prevent and reduce GERD by improving lung function, actively reducing weight and quitting smoking.