Exploring the value of high-resolution esophageal manometry(HRM) in analyzing the therapeutic effect of peroral endoscopic cardiac constriction(PECC) on gastroesophageal reflux disease(GERD).

Clinic data of sixty one patients with GERD who received PECC at the People's Hostital of Xinchang were retrospectively studied form January 2022 to December 2023. Analysis the correlation between endoscopic Hill grading, HRMexamination,patient self-rating anxiety scale (SAS) and self-rating depression scale(SDS)scores with the satisfaction of PECC on GERD.

There was no correlation (P>0.05) between the Hill grading, length of the lower esophageal sphincter, and pressure of the lower esophageal sphincter with the satisfaction in patients with Hill grading of Ⅰ-Ⅲ. However, there was a correlation (P<0.05) between esophageal peristalsis function, SAS and SDS scores with the satisfaction. Patients with normal SAS and SDS scores have a correlation between esophageal body peristalsis function with the satisfaction (P<0.05), while patients with abnormal SAS and/or SDS scores have no correlation between esophageal body peristalsis function with the satisfaction (P>0.05).

Hill grading of I-III is one of the indications for PECC on GERD. Esophageal peristalsis function and psychological factors are important influencing factors for the efficacy of PECC on GERD. HRM examination plays a significant role in preoperative evaluation and postoperative efficacy analysis of PECC.