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中华胃食管反流病电子杂志 ›› 2024, Vol. 11 ›› Issue (03) : 153 -158. doi: 10.3877/cma.j.issn.1672-6448.2024.03.007

综述

胃食管反流伴食管运动障碍的诊疗进展
刘虎1, 任振1, 韦笑韩2, 潘晨3, 吴立胜3,()   
  1. 1.233030 安徽,蚌埠医学院
    2.241002 安徽 芜湖,皖南医学院
    3.230001 合肥,中国科学技术大学附属第一医院(安徽省立医院)疝及减重代谢外科
  • 收稿日期:2024-03-10 出版日期:2024-08-15
  • 通信作者: 吴立胜
  • 基金资助:
    吴阶平医学基金会临床科研专项资助基金(2022-07-7)

Advancements in the diagnosis and treatment of gastroesophageal reflux disease with esophageal dysmotility

Hu Liu1, Zhen Ren1, Xiaohan Wei2, Chen Pan3, Lisheng Wu3,()   

  1. 1.Bengbu Medical College,Bengbu 233030,China
    2.Wannan Medical College,Wuhu 241002,China
    3.Department of Hernia and Bariatric Metabolic Surgery,the First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei 230001,China
  • Received:2024-03-10 Published:2024-08-15
  • Corresponding author: Lisheng Wu
引用本文:

刘虎, 任振, 韦笑韩, 潘晨, 吴立胜. 胃食管反流伴食管运动障碍的诊疗进展[J]. 中华胃食管反流病电子杂志, 2024, 11(03): 153-158.

Hu Liu, Zhen Ren, Xiaohan Wei, Chen Pan, Lisheng Wu. Advancements in the diagnosis and treatment of gastroesophageal reflux disease with esophageal dysmotility[J]. Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition), 2024, 11(03): 153-158.

胃食管反流伴食管运动障碍是一种发病率低的消化系统疾病。目前发病机制尚不明确。高分辨食管测压法是诊断胃食管反流病(GERD)伴食管运动障碍(ED)的首选方法,其他诊断方法包括内镜、食管钡餐造影等。在临床实践中,胃食管反流伴食管运动障碍可分为原发性和继发性。原发性中,贲门失弛缓症是一种相对常见的疾病;而在继发性疾病中,系统性硬化症较为常见。治疗胃食管反流伴食管运动障碍的治疗方法包括保守治疗和手术治疗,保守治疗包括内镜下注射肉毒毒素、服用5-羟色胺受体激动剂等;手术治疗针对原发性和继发性胃食管反流伴食管运动障碍采取不同的方法。原发性通常包括球囊扩张术、腹腔镜下贲门肌切开术和经口内镜下肌切开术等。而对于继发性,常见的手术方式包括腹腔镜下胃底折叠术、Roux-en-Y 胃旁路术、电刺激疗法和腹腔镜磁环括约肌增强术等。本综述旨在探讨胃食管反流伴食管运动障碍的诊疗进展,为临床实践和未来研究提供参考和指导。

Gastroesophageal reflux with esophageal dysmotility is a low-incidence digestive system disease. The pathogenesis is currently unclear.High-resolution manometry is the preferred method for diagnosing gastroesophageal reflux disease (GERD) and esophageal dysmotility (ED). Other diagnostic methods include endoscopy and barium swallow imaging of the esophagus.In clinical practice, GERD and ED can be classified as primary and secondary. In primary cases, achalasia is a relatively common condition,while in secondary diseases, systemic sclerosis is more prevalent.Treatment for GERD and ED includes conservative and surgical options. Conservative treatment methods include endoscopic botulinum toxin injection and the use of 5-HT receptor agonists.Surgical treatment adopts different methods for primary and secondary GERD with ED. Primary GERD typically includes procedures such as pneumatic dilation,laparoscopic Heller myotomy, and peroral endoscopic myotomy.For secondary GERD and ED, common surgical methods include laparoscopic fundoplication, Roux-en-Y gastric bypass surgery, electrical stimulation therapy,and laparoscopic magnetic sphincter augmentation.This review aims to explore the progress in the diagnosis and treatment of GERD and ED, providing references and guidance for clinical practice and future research.

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