Analysis of clinical effect of esophagus low-level radiofrequency in treatment of gastroesophageal reflux disease patients associated with nasal symptoms

doi:10.3877/cma.j.issn.1674-6899.2016.03.002

Abstract

Abstract:

Objective

To observe the efficacy of low-level radiofrequency in treatment of gastroesophageal reflux disease(GERD)patients associated with nasal symptoms.

Methods

370 patients with GERD who underwent radiofrequency treatment during April 2006 to July 2007 were enrolled, and the nasal symptoms in the patients were analyzed before and after treatment.

Results

Among the 370 patients, 120 patients(32.4%)were associated with nasal symptoms, including watery nasal discharge, sneeze, nasal obstruction, snore, post nasal drip, and other discomfort.After treatment, the scores of different nasal symptom were lower than before treatment, and the differences were significant(P<0.01). The nasal symptom improved in 70 cases(59.9%), and the efficacy rate in the patients was 19.9% to 29.2%, remission rate was 27.8% to 50%, and inefficiency rate was 25% to 52.2%.

Conclusion

GERD can cause nasal symptoms, and esophagus low-level radiofrequency treatment is effective.

Key words: Gastroesophageal reflux, Nasal, Radiofrequency therapy

Changrong Deng, Jimin Wu, Shurui Tian, Zhonggao Wang, Jianjun Liu, Zhiwei Hu, Feng Wang, Tao Ji, Xiulan Zhan, Yu Zhang, Songsong Ma. Analysis of clinical effect of esophagus low-level radiofrequency in treatment of gastroesophageal reflux disease patients associated with nasal symptoms[J]. Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition), 2016, 03(03): 110-113.

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Figures/Tables 3

References 23

1	汪忠镐．胃食管反流病不容忽视—谈中老年胃食管反流病[J]．临床误诊误治，2006，19(5):1-2.
2	汪忠镐，刘建军，陈秀，等．胃食管喉气管综合征(GELTS)的发现与命名—Stretta射频治疗胃食管反流病200例[J]．临床误诊误治，2007，20(5):1-4.
3	Contenein P, Narcy P．Nasopharyngeal pH monitoring in infants and children with chronic rhinopharyngitis[J]．Int J Pediatr Otorhinolaryngol，1991，22(3):249-256.
4	Yellon RF, Coticchia J, Dixit S．Esophageal biopsy for the diagnosis of gastroesophageal reflux-associated otolaryngologic problems in children[J]．Am J Med，2000，108(4):131S-138S.
5	Philip O, Katz MD, Lauren B，et al.Guidelines for the Diagnosis and Management of Gastroesophageal Reflux Disease[J]．Am J Gastroenterol，2013，108:308-328.
6	Poelmans J, Tack J．Extraoesophageal manifestations of gastro-oesophageal reflux[J]．Gut，2005，54(10):1492-1499.
7	Chen CL, Hsu PI.Current advances in the diagnosis and treatment of nonerosive reflux disease[J]．Gastroenterol ResPract，2013，2013:653-989.
8	Domingues GR, Moraes-Filho JP, Domingues AG.Impact of prolonged 48h wireless capsule esophageal pH monitoring on diagnosis of gastroesophageal reflux disease and evaluation of the relationship between symptoms and reflux episodes[J]．Arq Gastroenterol，2011，48(1):24-29.
9	Sifrim D, Fornari F．Esophageal impedan ce-pH monitoring[J]．Dig Liver Dis.2008，40(3):161-166.
10	Iwakiri K, Kobayashi M, Kotoyori M，et al.Relationship between postprandial esophageal acid exposure and meal volume and fat content[J]．Dig Dis Sci，1996，41(5):926-930.
11	Feldman M, Barnett C．Relationships between the acidity and osmolality of popular beverages and reported postprandial heartburn[J]．Gastroenterology，1995，108(1):125-131.
12	Duroux P, Bauerfeind P, Emde C．Early dinner reduces nocturnal gastric acidity[J]．Gut，1989，30(8):1063-1067.
13	吴欢，柯美云．改变不良生活方式和饮食习惯在胃食管反流病治疗中的作用[J]．胃肠病学，2009，14(8):449-452.
14	Bothwell MR, Parsons DS, Talbot A，et al.Outcome of reflux therapy on pediatric chronic sinusitis[J]．Otolaryngol Head Neck Surg，1999，121(3):255-262.
15	Phipps CD, Wood WE, Gibson WS，et al.Gastroe-sophageal reflux contributing to chronic sinus disease in children：a prospective analysis[J]．Arch Otolaryngol Head Neck sury，2000，126(7):831-836.
16	Tam WCE, Schoeman MN, Zhang Q，et al.Delivery of radiofrequency energy(RFe)to the lower esophageal sphincter(LES)and gastric cardia inhibits transient LES relaxation and gastroesophageal reflux in patients with reflux disease[J]．Gastroenterology，2001，120(1):77-83.
17	汪忠镐．胃食管反流病的微创治疗进展[J]．中国微创外科杂志，2006，6(10):721-724.
18	Pleskow D, Rothstein R, Lo S，et al.Endoscopic fu11-thickness plication for the treatment of GERD：12-months follow-up for the North American open-label tria1[J]．Gastrointest Endosc，2005，61:643-649.
19	Schiefke I, Zabel-Langhennig A, Neumann S，et al.Long term failure of endoscopic gastroplication(EndoCinch)[J]．Gut，2005，54:752-758.
20	Johnson DA, Ganz T, Aisenberg J，et al.Endoscopic implantation of Enteryx for treatment of GERD：12 month results of a prospective multicenter trail[J]．Am J Gastroenterol，2003，98:1921-1930.
21	Chuttani R, Sud R, Sachdey G，et al.A novel endoscopopic full-thickness plicator for the treatment of GERD[J]：a pilot study.Gastrointest Endosc，2003，58:770-776.
22	Geagea T．Laparoscopic Nissen′s fundoplication：preliminary report on ten cases[J]．Surg Endosc，1991，5:170-173.
23	胡志伟，汪忠镐，吴继敏，等．胃食管反流病合并食管裂孔疝及哮喘症状的腹腔镜外科治疗[J/CD]．中华疝和腹壁外科杂志，2014，8(5):396-403.

组别	例数	流清涕	打喷嚏	鼻噻	打鼾	鼻滴后流	其他
治疗前	117	1.88±0.74	1.85±0.68	1.94±0.64	1.63±0.77	2.13±0.72	2.00±0.69
治疗后	117	0.96±0.76	0.93±0.66	0.96±0.71	0.93±0.57	1.06±0.85	0.94±0.73
t值	?	9.003	7.516	7.136	5.449	4.977	3.855
P值	?	0.000	0.000	0.000	0.000	0.000	0.001

组别	例数	流清涕	打喷嚏	鼻噻	打鼾	鼻滴后流	其他
治疗前	117	1.88±0.74	1.85±0.68	1.94±0.64	1.63±0.77	2.13±0.72	2.00±0.69
治疗后	117	0.96±0.76	0.93±0.66	0.96±0.71	0.93±0.57	1.06±0.85	0.94±0.73
t值	?	9.003	7.516	7.136	5.449	4.977	3.855
P值	?	0.000	0.000	0.000	0.000	0.000	0.001

症状	例数	显效	缓解	无效
流清涕	72	19(26.4)	27(37.5)	26(36.1)
打喷嚏	55	14(25.5)	20(36.4)	21(38.2)
鼻塞	48	14(29.2)	16(33.3)	18(37.5)
打鼾	46	9(19.6)	13(28.3)	24(52.2)
鼻滴后流	16	4(25.0)	8(50.0)	4(25.0)
其他	18	5(27.8)	5(27.8)	8(44.4)

症状	例数	显效	缓解	无效
流清涕	72	19(26.4)	27(37.5)	26(36.1)
打喷嚏	55	14(25.5)	20(36.4)	21(38.2)
鼻塞	48	14(29.2)	16(33.3)	18(37.5)
打鼾	46	9(19.6)	13(28.3)	24(52.2)
鼻滴后流	16	4(25.0)	8(50.0)	4(25.0)
其他	18	5(27.8)	5(27.8)	8(44.4)

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