The effect of endoscopic mucosal resection with ligation for intestinal metaplasia of Barrett′s esophagus

doi:10.3877/cma.j.issn.1674-6899.2017.04.005

Abstract

Abstract:

Objective

To evaluate the efficacy and safety of Endoscopic mucosal resection with ligation(EMRL)for the treatment of Barrett′s esophagus(intestinal metaplasia).

Methods

Retrospective analysis of Gastroenterology from April 2014 to April 2016 endoscopy and pathology confirmed Barrett esophagus(intestinal type)45 patients with EMRL.To observe the clinical characteristics of patients, The rates of complications and following treatments were recorded, review endoscopy after 6 months to evaluate the curative effect.

Results

The main symptoms of 45 patients were upper abdominal discomfort, posterior sternal discomfort, acid reflux, 17 patients(37.8%)patients without GRED symptoms.All the lesions were resected in one time.The complications included sternal discomfort in 5 cases, upper abdominal discomfort in 3 cases and esophageal perforation in 1 case.

Conclusion

Endoscopic mucosal resection with ligation is safe and effective in the treatment of Barrett ′s esophagus(intestinal metaplasia). However, multicenter, large-scale randomized controlled studies are still needed.

Key words: Barrett′s esophagus, Intestinal metaplasia, Endoscopic mucosal resection with ligation

Huan He, Wenjie Kong, Feng Gao. The effect of endoscopic mucosal resection with ligation for intestinal metaplasia of Barrett′s esophagus[J]. Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition), 2017, 04(04): 161-164.

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