Home    中文  
 
  • Search
  • lucene Search
  • Citation
  • Fig/Tab
  • Adv Search
Just Accepted  |  Current Issue  |  Archive  |  Featured Articles  |  Most Read  |  Most Download  |  Most Cited

Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition) ›› 2017, Vol. 04 ›› Issue (04): 165-168. doi: 10.3877/cma.j.issn.1674-6899.2017.04.006

Special Issue:

• Original Article • Previous Articles     Next Articles

The effect of esophageal acid exposure on airway responsiveness and pulmonary function in asthmatic females

Aikemu Batuer·1, Halifu Gulipali·1, Abudureyimu Kelimu·1,()   

  1. 1. Department of Minimally Invasive Surgery, Hernia and Abdominal Wall Surgery, People′s Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China
  • Received:2017-10-22 Online:2017-11-15 Published:2017-11-15
  • Contact: Abudureyimu Kelimu·
  • About author:
    Corresponding author: Kelimu·Abudureyimu, Email:

Abstract:

Objective

To explore the corelation between different types of esophageal exposure and airway responsiveness and pulmonary funtion through 24-hour ambulatory pH monitoring, bronchial provocation test and pulmonary function test on asthmatic females.

Methods

All selected 36 female asmatic patients were devided into 2 groups based on whether their DeMeester scores in pH monitoring tests were higher than 14.72 or not.Analyse the Dmin score, pulmonary function and the type and severity of acid exposure.

Results

The Dmin score, FEV1% predicted, FEV1/FVC, FVC% predicted, RV/TLC showed no statistical difference between 15-sample GERD group and 21-sample Non Gerd group(P>0.05), nor did times of weak acidic(4<pH<7)reflux, total reflux episodes, supine or upright relux episodes, percentage of proximal reflux(P>0.05). But the acidic(pH≤4)reflux events in patients with GERD ware greater than those without GERD(P<0.05).

Conclusion

Our findings suggest that GERD, especcially associated with typically acidic reflux, does not aggravate the status of airway hyperresponsiveness or the pulmonary function in asmatic females.

Key words: Gastroesophageal reflux, Asthma, 24 h pH Monitoring, Airway hyperresponsiveness, Respiratory function tests

京ICP 备07035254号-20
Copyright © Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition), All Rights Reserved.
Tel: 0991-8563812 E-mail: zhwsgflbzz@163.com
Powered by Beijing Magtech Co. Ltd