Research advances on the role of ineffective esophageal motility in gastroesophageal reflux disease

doi:10.3877/cma.j.issn.2095-8765.2021.01.007

Abstract

Abstract:

Gastroesophageal reflux disease (GERD) is a clinically common gastrointestinal motility disorder, and esophageal motility disorder is one of its main pathogenesis. Ineffective esophageal motility (IEM) is the most common type of esophageal motility disorder in GERD. The role of IEM in the pathogenesis of GERD is still controversial. This article summarizes the pathophysiology, clinical features, dynamic characteristics and relationship with acid exposure of IEM, and its role in GERD. It provides new ideas and clues for further research on the role of IEM and guiding clinical treatment of GERD.

Key words: ineffective esophageal motility, gastroesophageal reflux disease, high-resolution manometry, acid exposure

Xi Zhao, Yang Shi, Dan. Wang. Research advances on the role of ineffective esophageal motility in gastroesophageal reflux disease[J]. Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition), 2021, 08(01): 37-41.

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