Effect of gastroesophageal reflux disease on lung function in patients with asthma

doi:10.3877/cma.j.issn.1674-6899.2018.02.005

Abstract

Abstract:

Objective

To investigate the effect of gastroesophageal reflux disease on lung function in patients with asthma.

Methods

There were admitted to Department of respiration and diagnosed asthma patients 226 cases who from May 2015 to August 2017 in the people′s hospital of Xinjiang Uygur Autonomous Region, according to whether complicated with GERD were divided into GERD group and non GERD group, compared two groups of patients with FEV1%, FVC% and FEV1/FVC% pulmonary function index.

Results

The incidence of GERD was 45.1%(102/226), GERD group of FEV1 %, FVC% and FEV1/FVC% were significantly lower than non GERD group, and the difference was statistically significant(P<0.05).

Conclusion

GERD is closely related with asthma, GERD has great influence on the pulmonary function of asthma patients, GERD and asthma is causal or accompanying relationship still need further study.

Key words: Gastroesophageal reflux, Asthma, Pulmonary function

Halike Maierhaba·, Alimu Maimaiti·, Xiaohong Yang. Effect of gastroesophageal reflux disease on lung function in patients with asthma[J]. Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition), 2018, 05(02): 65-67.

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References 18

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组别	例数	FEV1占预计值%	FVC占预计值%	FEV1/ FVC%
GERD组	102	68.4±18.9	74.4±17.6	63.4±10.8
非GERD组	124	82.6±12.7	89.2±16.5	72.2±7.9
t值	?	2.821	5.762	2.228
P值	?	0.029	<0.0001	0.039

组别	例数	FEV1占预计值%	FVC占预计值%	FEV1/ FVC%
GERD组	102	68.4±18.9	74.4±17.6	63.4±10.8
非GERD组	124	82.6±12.7	89.2±16.5	72.2±7.9
t值	?	2.821	5.762	2.228
P值	?	0.029	<0.0001	0.039

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