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中华胃食管反流病电子杂志

中华胃食管反流病电子杂志 ›› 2022, Vol. 09 ›› Issue (01) : 35 -38. doi: 10.3877/cma.j.issn.2095-8765.2022.01.007

综述

2型糖尿病与胃食管反流病的相关性研究进展
迪丽达尔·阿迪里1, 买买提·依斯热依力2, 艾克拜尔·艾力3,†()   
  1. 1. 830054　乌鲁木齐，新疆医科大学研究生学院
    2. 830001　乌鲁木齐，新疆维吾尔自治区人民医院微创，疝和腹壁外科；830001　乌鲁木齐，新疆维吾尔自治区人民医院自治区普外微创研究所；830001　乌鲁木齐，新疆维吾尔自治区胃食管反流病及减重代谢外科临床研究中心
    3. 830054　乌鲁木齐，新疆医科大学研究生学院；830001　乌鲁木齐，新疆维吾尔自治区人民医院微创，疝和腹壁外科；830001　乌鲁木齐，新疆维吾尔自治区人民医院自治区普外微创研究所；830001　乌鲁木齐，新疆维吾尔自治区胃食管反流病及减重代谢外科临床研究中心
  • 收稿日期:2021-05-12 出版日期:2022-02-15
  • 通信作者: 艾克拜尔·艾力
  • 基金资助:
    国家自然科学基金项目(82060166); 新疆维吾尔自治区引进高层次人才天池百人计划项目(201939); 新疆维吾尔自治区自然科学基金(2021D01C148)

Research progress of correlation between type 2 diabetes mellitus and gastroesophageal reflux disease

Dilidaer·Adili1, Maimaiti·Yisireyili2, Aikebaier·Aili3,†()   

  1. 1. Xinjiang Medical University Graduate School of Medicine, Urumqi 830054, China
    2. Department of Minimally Invasive Surgery, Hernia and Abdominal Wall Surgery, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China; Research Institute of General and Minimally Invasive Surgery, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China; Xinjiang Uygur Autonomous Region Gastroesophageal Reflux Disease and Weight Loss Metabolism Surgery Clinical Research Center, Urumqi 830001, China
    3. Xinjiang Medical University Graduate School of Medicine, Urumqi 830054, China; Department of Minimally Invasive Surgery, Hernia and Abdominal Wall Surgery, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China; Research Institute of General and Minimally Invasive Surgery, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China; Xinjiang Uygur Autonomous Region Gastroesophageal Reflux Disease and Weight Loss Metabolism Surgery Clinical Research Center, Urumqi 830001, China
  • Received:2021-05-12 Published:2022-02-15
  • Corresponding author: Aikebaier·Aili
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迪丽达尔·阿迪里, 买买提·依斯热依力, 艾克拜尔·艾力. 2型糖尿病与胃食管反流病的相关性研究进展[J]. 中华胃食管反流病电子杂志, 2022, 09(01): 35-38.

Dilidaer·Adili, Maimaiti·Yisireyili, Aikebaier·Aili. Research progress of correlation between type 2 diabetes mellitus and gastroesophageal reflux disease[J]. Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition), 2022, 09(01): 35-38.

2型糖尿病（T2DM）是目前发病率较高的代谢相关疾病，胃食管反流病（GERD）是发病率较高的消化道疾病之一，GERD被认为是T2DM并发症中慢性胃肠道疾病之一。T2DM和GERD的发生发展机制目前尚未研究明确，T2DM并发GERD患者影响食管动力学功能可能与胰岛素抵抗、高血糖、自主神经病变、胃肠激素、一过性下食管括约肌松弛及糖尿病药物使用有关，本文主要以T2DM与GERD相关性研究进展作以总结叙述。

关键词: 2型糖尿病, 胃食管反流病, 总结

The incidence rate of type 2 diabetes millutes (T2DM) and gastroesophageal reflux disease (GERD) rising in recent years. GERD was thought to be a one of the most chronic gastrointestinal diseases that often occurs in diabetic complications. The mechanism of DM and GERD unclear at present. The influence of esophageal dynamic function in DM complicated with GERD may related to insulin resistance, hyperglycemic autonomic neuropathy, gastrointestinal hormone, transient lower esophageal sphincter relaxation, and diabetic drug use. This article mainly summarizes the research progress of the relationship between DM and GERD.

Key words: Type 2 diabetes millutes, Gastroesophageal reflux diseases, Review
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