The value of wireless pH capsule monitoring in the diagnosis of laryngopharyngeal reflux

doi:10.3877/cma.j.issn.1674-6899.2015.04.002

Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition) ›› 2015, Vol. 02 ›› Issue (04): 197-201. doi: 10.3877/cma.j.issn.1674-6899.2015.04.002

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The value of wireless pH capsule monitoring in the diagnosis of laryngopharyngeal reflux

Jiawei Chen¹, Longping Chen², Dazhou Li², Rong Wang², Chuanshen Jiang², Linfu Zheng², Wen Wang²^,^†()

^1. Clinical College of Fuzhou General Hospital, Anhui Medical University, Hefei 230001, China; Department of Gastroenterology, Fuzhou General Hospital of Nanjing Military Command, Fuzhou 350025, China
^2. Department of Gastroenterology, Fuzhou General Hospital of Nanjing Military Command, Fuzhou 350025, China

Received:2015-10-13 Online:2015-11-15 Published:2015-11-15
Contact: Wen Wang
About author:
Corresponding author: Wang Wen, Email: wangw68@medmail.com.cn

Abstract

Abstract:

Objective

To investigate the correlation between gastroesophageal reflux and laryngopharyngeal reflux(LPR)and the clincal value of wireless pH capsule monitoring in the diagnosis of LPR.

Methods

Tweleve patients with LPR symptoms who scored more than 13 in reflux symptoms index(RSI)test and tweleve healthy volunteers were recruited.They were required to receive RSI test and 48-hour dual wireless pH monitoring.The details of meals, sleep, activities, and discomfort were recorded.The acid exposure and the correlation of proximal and distal esophageal were analyzed.

Results

The LPR episodes and DMS in LPR patients were significantly higher than that in healthy volunteer group(P<0.05), in coincidence with the RSI scores.The LPR episodes were correlated with DMS in LPR patients significantly.There were not any severe side effects during monitoring.

Conclusion

Wireless pH capsule is effective in pH monitoring in laryngopharyngeal reflux with high accuracy, safety and tolerance.

Key words: Laryngopharyngeal reflux, Wireless pH capsule

Jiawei Chen, Longping Chen, Dazhou Li, Rong Wang, Chuanshen Jiang, Linfu Zheng, Wen Wang. The value of wireless pH capsule monitoring in the diagnosis of laryngopharyngeal reflux[J]. Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition), 2015, 02(04): 197-201.

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Figures/Tables 4

References 24

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参数	RSI评分	咽喉反流次数	DMS
对照组	5.00±2.40	1.00±0.95	4.80±3.43
LPR组	16.75±3.08	10.17±5.73	27.39±10.57
P值	<0.001	<0.001	<0.001

参数	RSI评分	咽喉反流次数	DMS
对照组	5.00±2.40	1.00±0.95	4.80±3.43
LPR组	16.75±3.08	10.17±5.73	27.39±10.57
P值	<0.001	<0.001	<0.001

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