Oral pH changes in patients with gastroesophageal reflux disease

doi:10.3877/cma.j.issn.2095-8765.2018.03.004

Abstract

Abstract:

Objective

To compare the pH value of various oral mucosa and the salivary buffer capacity between patients with gastroesophageal reflux disease (GERD) and healthy controls.

Methods

The pH value of different oral mucosa and salivary buffer capacity were tested in 30 patients with gastroesophageal reflux by using the two-point test method through precise pH testing paper, and compared with 34 healthy people.

Results

A significantly lower pH of 6.38 ± 0.33 was found in the GERD group compared to control group 7.11±0.17, and the saliva buffer capacity (SBC) of GERD group was 3.37±0.29, which was significantly lower than the control group 5.07±0.23. There was a difference in the pH value of the oral cavity in GERD group at different time, least pH was found in the floor of the mouth at 9:00 am to 11:00 am, and highest in the hard palate mucosa at 2:30 pm to 4:30 pm.

Conclusion

The oral cavity of gastroesophageal reflux patients is acidic, and the abnormal pH value should be corrected according to the specific conditions of oral cavity, in order to prevent the occurrence of oral complications.

Key words: Oral pH, Gastroesophageal reflux disease, Salivary buffer capacity, Dental erosion, Oral mucosa

Aji Yaerken·, Jie Liu, Xiaotao Chen, Huojia Muhetaer·, Xianghong Dang. Oral pH changes in patients with gastroesophageal reflux disease[J]. Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition), 2018, 05(03): 109-112.

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Figures/Tables 2

References 10

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检测指标	GERD组		对照组
检测指标	上午9：00~ 11：00	下午2：30~ 4：30	上午9：00~ 11：00	下午2：30~ 4：30
pH值	6.22±0.27	6.54±0.30	7.12±0.17	7.14±0.16
SBC值	3.36±0.23	3.39±0.19	5.06±0.28	5.08±0.22

检测指标	GERD组		对照组
检测指标	上午9：00~ 11：00	下午2：30~ 4：30	上午9：00~ 11：00	下午2：30~ 4：30
pH值	6.22±0.27	6.54±0.30	7.12±0.17	7.14±0.16
SBC值	3.36±0.23	3.39±0.19	5.06±0.28	5.08±0.22

部位	GERD组		对照组
部位	上午9：00~ 11：00	下午2：30~ 4：30	上午9：00~ 11：00	下午2：30~ 4：30
舌黏膜	6.03±0.18	6.61±0.12	7.15±0.21	7.16±0.15
硬腭黏膜	6.72±0.13	6.75±0.15	7.15±0.15	7.16±0.13
口底黏膜	6.00±0.10	6.11±0.15	7.03±0.17	7.04±0.17
左颊黏膜	6.33±0.12	6.39±0.13	7.07±0.14	7.08±0.13
右颊黏膜	6.33±0.11	6.38±0.12	7.07±0.13	7.08±0.12
上唇黏膜	6.12±0.11	6.61±0.14	7.06±0.15	7.07±0.15
下唇黏膜	6.05±0.12	6.95±0.27	7.19±0.12	7.25±0.13

部位	GERD组		对照组
部位	上午9：00~ 11：00	下午2：30~ 4：30	上午9：00~ 11：00	下午2：30~ 4：30
舌黏膜	6.03±0.18	6.61±0.12	7.15±0.21	7.16±0.15
硬腭黏膜	6.72±0.13	6.75±0.15	7.15±0.15	7.16±0.13
口底黏膜	6.00±0.10	6.11±0.15	7.03±0.17	7.04±0.17
左颊黏膜	6.33±0.12	6.39±0.13	7.07±0.14	7.08±0.13
右颊黏膜	6.33±0.11	6.38±0.12	7.07±0.13	7.08±0.12
上唇黏膜	6.12±0.11	6.61±0.14	7.06±0.15	7.07±0.15
下唇黏膜	6.05±0.12	6.95±0.27	7.19±0.12	7.25±0.13

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