切换至 "中华医学电子期刊资源库"

中华胃食管反流病电子杂志 ›› 2018, Vol. 05 ›› Issue (02) : 61 -64. doi: 10.3877/cma.j.issn.1674-6899.2018.02.004

所属专题: 经典病例 文献

论著

胃食管反流为主要症状的先天性肠旋转不良65例诊疗经验
和军1, 颜景灏2, 姚海霞1, 刘妍芳1, 阿布都赛米·阿不都热依木1, 周玲1, 王洁1, 李水学1,()   
  1. 1. 830000 乌鲁木齐,新疆维吾尔自治区人民医院小儿外科;830000 乌鲁木齐,新疆维吾尔自治区儿童医院小儿外科
    2. 830000 乌鲁木齐,新疆维吾尔自治区人民医院小儿外科;830000 乌鲁木齐,新疆维吾尔自治区儿童医院小儿外科;830000 乌鲁木齐,新疆医科大学研究生学院
  • 收稿日期:2018-02-19 出版日期:2018-05-15
  • 通信作者: 李水学
  • 基金资助:
    卫计委公益性行业专项(201402007)

Gastroesophageal reflux as the main symptom of congenital intestinal dysplasia 65 cases of treatment experience

Jun He1, Jinghao Yan2, Haixia Yao1, Yanfang Liu1, Abudoureyimu Abudousaimi·1, Lin Zhou1, Jie Wang1, Shuixue Li1,()   

  1. 1. Department of Pediatric Surgery, People′s Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830000, China; Department of Pediatric Surgery, Xinjiang Uygur Autonomous Region Children′s Hospital, Urumqi 830000, China
    2. Department of Pediatric Surgery, People′s Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830000, China; Department of Pediatric Surgery, Xinjiang Uygur Autonomous Region Children′s Hospital, Urumqi 830000, China; Xinjiang Medical University Graduate School, Urumqi 830000, China
  • Received:2018-02-19 Published:2018-05-15
  • Corresponding author: Shuixue Li
  • About author:
    Corresponding author: Li Shuixue, Email:
引用本文:

和军, 颜景灏, 姚海霞, 刘妍芳, 阿布都赛米·阿不都热依木, 周玲, 王洁, 李水学. 胃食管反流为主要症状的先天性肠旋转不良65例诊疗经验[J]. 中华胃食管反流病电子杂志, 2018, 05(02): 61-64.

Jun He, Jinghao Yan, Haixia Yao, Yanfang Liu, Abudoureyimu Abudousaimi·, Lin Zhou, Jie Wang, Shuixue Li. Gastroesophageal reflux as the main symptom of congenital intestinal dysplasia 65 cases of treatment experience[J]. Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition), 2018, 05(02): 61-64.

目的

探讨新生儿期先天性肠旋转不良的临床特征,治疗方法及预后情况。

方法

回顾性分析2008年12月至2017年12月,新疆维吾尔自治区人民医院小儿外科收治的新生儿先天性肠旋转不良65例患儿的临床资料。65例患儿手术年龄2~28 d平均手术年龄(7±1.2)d,所有患儿均通过术中或术前辅助检查证实为先天性肠旋转不良。60例出生后即出现间断性呕吐并伴胃食管反流,55例为间断性胆汁性呕吐,5例出现便血。所有患儿术前均行超声检查,阳性例数为45例。60例术前行消化道造影,阳性率92%。65例均行Ladd′s手术治疗。

结果

65例新生儿肠旋转不良患儿均术中证实先天性肠旋转不良,其中中肠扭转5例,2例有中肠扭转、中肠坏死,行肠切除肠吻合。65例患儿中合并先天性乳糜腹1例,合并其他消化道畸形20例。中肠扭转的患儿临床特点为血便、膜炎体征。

结论

间断性呕吐伴胃食管反流为先天性肠旋转不良的主要表现,血便合并腹膜炎体征是急诊手术的明确指征。消化道造影阳性率较超声更准确。新生儿期先天性肠旋转不良一经确诊早期行Ladd′s手术效果好,预后良好。

Objective

To explore the clinical features, treatment and prognosis of neonatal congenital intestinal malrotation.

Methods

From December 2008 to December 2017, 65 patients were treated for malrotation of intestine in People′s Hospital of Xinjiang Uygur Autonomous Region pediatric surgery.65 cases, of children surgical age is 2days to 28 days(the mean operative age was 7±1.2 days). All children were confirmed as congenital intestinal malrotation by intraoperative or preoperative auxiliary examination.Sixty patients developed intermittent vomiting with gastroesophageal reflux after birth.55 patients were intermittent biliary vomiting.Five patients showed hematochezia.All children underwent color Doppler examination before surgery.There were 45 cases of positive.60 patients completed digestive angiography before surgery.There were 92% of positive.Sixty-five patients underwent Ladd′s surgery.

Results

Sixty-five patients confirmed congenital intestinal malrotation during surgery.There are 5 patients with midgut torsion.2 cases had intestinal torsion and intestinal necrosis, accepted intestinal resection of intestinal anastomosis.One patient had congenital chylomicrons.Twenty patients combined with other gastrointestinal malformations.Intestinal torsion in children with clinical features are bloody stools, meningitis signs.

Conclusion

Intermittent vomiting with gastroesophageal reflux is the main manifestation of congenital intestinal malrotation.Bloody stool with peritonitis signs is a clear indication of emergency surgery.Gastrointestinal imaging is more accurate than color Doppler.Neonatal congenital intestinal malrotation complete Ladd surgery in time.Surgical effect is good, the prognosis is good.

图3 术后腹部平片
1
周崇高, 李碧香, 王海阳, 等. 新生儿肠旋转不良并中肠扭转的微创手术治疗[J]. 临床小儿外科杂志, 2016, (15):167-169.
2
刘会锋, 孙忠源, 王献良. 新生儿肠旋转不良139例诊治经验[J]. 中国继续医学教育, 2016, 28(8):109-111.
3
Nasir AA, Abdur-Rahman LO, Adeniran JO.Outcomes of surgical treatment of malrotation in children[J]. J Paediatr Surg, 2011, 8(1):8-11.
4
Hamidi H, Obaidy Y, Maroof S. Intestinal malrotation and midgut volvulus[J]. Radiol Case Rep, 2016, 22, 11(3):271-274.
5
Khatami A, Mahdavi K, Karimi MA.Ultrasound as a feasible method for the assessment of malrotation[J]. Pol J Radiol, 2014, 19(79):112-116.
6
Brinkley MF, Tracy ET, Maxfield CM.Congenital duodenal obstruction:causes and imaging approach[J]. Pediatr Radiol, 2016, 46(8):1084-1095.
7
郑珊.实用新生儿外科学[M].北京:人民卫生出版社,2013.424-429.
8
Hasosah MY, Meer WI, Alsaleem K. Intestinal Volvulus:A Life?Threatening Disease[J]. J Clin Diagn Res, 2016, 10(3):SJ01.
9
米荣, 康利民, 马继东, 等. 先天性肠旋转不良84例. 实用儿科杂志, 2012, 27(15):1204-1206.
10
Morikawa N, Kuroda T, Honna T, et a1.A novel association of duodenal atresia, malrotation, segmental dilatation of the colon, and anorectal malformation[J]. Pediatr SurgInt, 2009, 25(11):1003-1005.
11
Lodwick DL, Minneci PC, Deans KJ.Current surgical management of intestinal rotational abnormalities[J]. Curr Opin Pediatr, 2015, 27(3):383-388.
12
Zhan J, Feng J, Chen Y, et al.Incidence of biliary atresia associated congenital malformations:A retrospective multicenter study in China[J]. Asian J Surg, 2017, 40(6):429-433.
13
李炳, 陈卫兵, 王寿青, 等. 腹腔镜诊治复杂型肠旋转不良七例][J]. 中华小儿外科杂志, 2015, 36(11):829-832.
14
Long L, Zhen C, Yandong W, et al.Congenital chylous ascites in infants:another presentation of intestinal malrotation[J]. J Pediatr Surg, 2018, 53(3):537-539.
15
Mitsunaga T, Saito T, Terui K, et al.Risk Factors for Intestinal Obstruction After Ladd Procedure[J]. Pediatr Rep, 2015, 7(2):5795.
16
王春燕, 徐畅, 钟麟, 等. 新生儿肠旋转不良合并中肠扭转的诊治分析[J]. 临床小儿外科杂志, 2013, 12(1):58-60.
[1] 李世红, 侯康. 腹腔镜食管裂孔疝补片修补术联合胃底折叠术(Nissen)[J]. 中华普通外科学文献(电子版), 2023, 17(05): 365-365.
[2] 王鸿彬, 何晓, 吴菁宙. 腹腔镜近端胃切除术中背驮式间置空肠单通道重建术在AEG手术的安全性及抗反流效果研究[J]. 中华普外科手术学杂志(电子版), 2023, 17(05): 526-529.
[3] 赵国栋, 施喆, 孙树刚, 薛亮, 王晓辉, 杨勇. 两种消化道重建方案的腹腔镜近端胃切除术后患者胃内压变化的对比研究[J]. 中华普外科手术学杂志(电子版), 2023, 17(03): 292-295.
[4] 贾卓奇, 周维茹, 张勇, 张广健, 付军科. 达·芬奇机器人与腹腔镜食管裂孔疝修补术的对比研究[J]. 中华疝和腹壁外科杂志(电子版), 2023, 17(04): 410-414.
[5] 李玮佳, 李振方, 李聪, 张倩, 赵琦. 胃食管阀瓣分级在伴有食管外症状的反流性食管炎的分布特点及意义[J]. 中华消化病与影像杂志(电子版), 2023, 13(02): 68-72.
[6] 史亚东, 顾建平. 无症状肺栓塞的诊断与治疗进展[J]. 中华介入放射学电子杂志, 2023, 11(02): 155-158.
[7] 赵键, 孙法同, 邢宝杰, 王勇, 吕琳, 于雪淳, 王海滨, 贾代良. 肢体坏死性筋膜炎的诊断学特征并文献复习[J]. 中华诊断学电子杂志, 2023, 11(02): 87-91.
[8] 张继舜, 陈思旭, 钱洁, 尚占民, 郝建宇. 平均夜间基线阻抗对食管外症状胃食管反流病的临床诊断价值[J]. 中华胃肠内镜电子杂志, 2023, 10(02): 97-102.
[9] 吕昆明, 王沙沙, 万军, 令狐恩强. 胃食管反流病与特发性肺纤维化关系的研究进展[J]. 中华胃肠内镜电子杂志, 2023, 10(02): 121-124.
[10] 陆洪鹏, 袁芯, 郑树灏, 刘怡, 徐磊. 慢性咳嗽与胃食管反流病:双向两样本孟德尔随机化研究[J]. 中华胃食管反流病电子杂志, 2023, 10(02): 59-64.
[11] 范勇, 张利昉, 杨美琳. 改良经口内镜下贲门缩窄术治疗胃食管反流病效果分析[J]. 中华胃食管反流病电子杂志, 2023, 10(02): 65-68.
[12] 文明, 熊英, 艾克拜尔·艾力, 克力木·阿不都热依木. 质子泵抑制剂治疗期间焦虑对胃食管反流病疗效的影响[J]. 中华胃食管反流病电子杂志, 2023, 10(02): 90-95.
[13] 李鹏, 刘国祥, 李汝红. 经口内镜下贲门缩窄术治疗胃食管反流病的研究进展[J]. 中华胃食管反流病电子杂志, 2023, 10(02): 96-99.
[14] 买买提·依斯热依力, 尹强, 尹海龙, 董雨微, 王永康, 克力木·阿不都热依木, 阿吉艾克拜尔·艾萨. 传统医药治疗胃食管反流病的研究进展[J]. 中华胃食管反流病电子杂志, 2023, 10(02): 100-104.
[15] 闫文貌, 孙海涛, 白日星. 胃袖状切除相关术式中应重视胃窦部解剖与生理功能[J]. 中华肥胖与代谢病电子杂志, 2023, 09(03): 161-164.
阅读次数
全文


摘要