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中华胃食管反流病电子杂志

中华胃食管反流病电子杂志 ›› 2022, Vol. 09 ›› Issue (04) : 204 -208. doi: 10.3877/cma.j.issn.2095-8765.2022.04.007

综述

药物与抗反流手术治疗胃食管反流病的对照研究进展
伊尔夏提江·艾尼瓦尔1, 买买提·依斯热依力2, 克力木·阿不都热依木3,†()   
  1. 1. 830001　乌鲁木齐，新疆医科大学研究生院
    2. 830001　乌鲁木齐，新疆维吾尔自治区人民医院普外微创研究所；830001　乌鲁木齐，新疆维吾尔自治区人民医院微创、疝和腹壁外科
    3. 830001　乌鲁木齐，新疆医科大学研究生院；830001　乌鲁木齐，新疆维吾尔自治区人民医院普外微创研究所；830001　乌鲁木齐，新疆维吾尔自治区人民医院微创、疝和腹壁外科
  • 收稿日期:2021-03-15 出版日期:2022-11-15
  • 通信作者: 克力木·阿不都热依木
  • 基金资助:
    国家自然科学基金项目(82060166); 新疆维吾尔自治区自然科学基金(2021D01C148)

Research progress of drug treatment and anti-reflux surgery in the treatment of gastroesophageal reflux disease

Yierxiatijiang·Ainiwaer1, Maimaiti·Yisireyili2, Kelimu·Abudureyimu3,†()   

  1. 1. Xinjiang Medical University, Xinjiang Uygur Autonomous Region, Urumqi 830001, China
    2. Research Institute of General and Minimally Invasive Surgery, Hernia and Abdominal Wall Surgery, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China; Department of Minimally Invasive Surgery, Hernia and Abdominal Wall Surgery, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China
    3. Xinjiang Medical University, Xinjiang Uygur Autonomous Region, Urumqi 830001, China; Research Institute of General and Minimally Invasive Surgery, Hernia and Abdominal Wall Surgery, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China; Department of Minimally Invasive Surgery, Hernia and Abdominal Wall Surgery, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China
  • Received:2021-03-15 Published:2022-11-15
  • Corresponding author: Kelimu·Abudureyimu
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伊尔夏提江·艾尼瓦尔, 买买提·依斯热依力, 克力木·阿不都热依木. 药物与抗反流手术治疗胃食管反流病的对照研究进展[J]. 中华胃食管反流病电子杂志, 2022, 09(04): 204-208.

Yierxiatijiang·Ainiwaer, Maimaiti·Yisireyili, Kelimu·Abudureyimu. Research progress of drug treatment and anti-reflux surgery in the treatment of gastroesophageal reflux disease[J]. Chinese Journal of Gastroesophageal Reflux Disease(Electronic Edition), 2022, 09(04): 204-208.

胃食管反流病（GERD）是消化系统常见疾病，发病率呈逐年上升趋势。目前GERD在临床上的一线治疗方法以改变生活方式和使用质子泵抑制剂为主，但由于药物治疗具有一定的局限性，对药物治疗无效的患者可选择内窥镜治疗和外科手术治疗。本文主要阐述了GERD的药物治疗、内窥镜治疗和外科手术治疗等方式的优缺点、适应人群以及不良反应，为患者提供更合适、更有效的治疗方法。

关键词: 胃食管反流病, 质子泵抑制剂, 抗反流手术

Gastroesophageal reflux disease(GERD)is a common disease of the digestive system, and its incidence is increasing year by year. At present, the first-line treatment of gastroesophageal reflux disease is mainly based on lifestyle modification and the use of proton pump inhibitors (PPI). However, due to the limitations of drug therapy, patients who do not respond to drug therapy can choose endoscopic therapy and surgery operation treatment. This article mainly describes the advantages and disadvantages, Indications and side effects of various treatment methods for GERD, so as to provide patients with more suitable and effective treatment methods.

Key words: Gastroesophageal reflux disease, Proton pump inhibitor, Anti-reflux surgery
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